100% Chitosan Haemostatic Dressing
Vascular Haemostatic Dressing
Axiostat is a sterile, non-absorbable haemostatic dressing intended to control bleeding within minutes of application by providing an active mechanical barrier to the wound site.
Cardiac patients are often at high-risk of uncontrolled bleeding due to the blood thinner/anti coagulants that are administered prior to catheterisation procedures. The vascular variant is effective on such patients during sheath removal. Axiostat controls femoral and radial arterial bleeding during vascular procedures.
Axiostat works on a principle of adhesion due to charge. Axiostat made with100% chitosan has been designed to be positively charged and blood cells carry a net negative charge. When blood comes in contact with Axiostat, oppositely charged components are attracted and form bonds. This results in a strong adhesive seal that acts as a mechanical barrier preventing blood from leaking out.
- Sterile, ready to use
- Hypoallergenic no known side-effects
- Active on all sides
Based on patented, clinically validated a.c.t (Axio clotting technology)
intended use / indication
Axiostat ® Vascular Haemostatic Dressing is a sterile, single use, non-absorbable haemostatic dressing intended to be used to control bleeding from vascular access sites while reducing ambulation time in patients who have undergone diagnostics or interventional endovascular procedures utilizing procedural sheath.
procedures (Radial Artery)
|Composition||Chitosan - 100%|
|Indication||Stops severe bleeding|
|Mechanism||Mucoadhesion due to change|
|Material||Positively charged, reacts actively|
|Type||Sponge, natural polymer|
|Flexibility||Very flexible, both sides active|
|Sterility||Sterilized using Gama irradiation|
|Shelf Life||3 Years|
|Removal||Irrigate with saline|
how to use axiostat
- Studying Hemostatic Effect of Axiostat® Dressing on Radial Access After Percutaneous Procedure (AHD). ClinicalTrials.gov Identifier: NCT02837744.
- Chitosan enhances platelet adhesion and aggregation. Chou TC. et al. Biochemical and Biophysical Research Communications; 2003, 302(3):480-3.
- Effect of chitosan molecular weight and deacetylation degree on hemostasis. Yang J. et al. Journal of Biomedical Material Research: Part B, Applied Biomaterials; 2008, 84(1):131-7.
- Percutaneous microcrystalline chitosan application for sealing arterial puncture sites. Hoekstra A, Struszczyk H, Kivekäs O. Biomaterials; 1998, 19(16):1467-71.
- A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. Achneck HE. et al., Annals of Surgery. 2010, 251(2):217-28.