VASCULAR
Axiostat - 100% Chitosan Haemostatic Dressing on Transfemoral Interventional Cardiology Procedure
Center
- Seth Sukhlal Karnani Medical Hospital, Kolkata-India
- Institute of Neurosciences, Kolkata-India
Patient details | 44 years , Male | 41 years , Male | 55 years , Male |
Patient history | Diabetes & Hypertension | No Diabetes & no Hypertension | Diabetes & no Hypertension |
Procedure | PTCA | DSA | PTCA |
Heparin dosage | 8000 IU | - | 8000 IU |
Sheath size | 6F | 5F | 6F |
Loading dose | Clopidogrel 300 mg | - | Clopidogrel 300 mg |
Axiostat Variant | V55 | V55 | V55 |
Average time taken to achieve haemostasis | 6 mins | 5 mins | 5 mins |
The sheath was removed carefully from the access site
Axiostat was placed on the puncture from where the blood was oozing out
The pressure was applied firmly on the puncture location for 5 mins
Axiostat was removed by irrigating with saline & disposed later.Puncture site was cleaned
Result
Patient Outcome with Axiostat | Ease of Application | Ease of Removal | Antimicrobial barrier | Adherence to Wound | Conformability of Dressing | Patient dressing |
Excellent | ✓ | ✓ | ✓ | ✓ | ✓ | |
Good | ✓ | |||||
Fair | ||||||
Poor |
Discussion
- The average time to achieve haemostasis in PTCA patients was 5.5mins (n=2), whereas, for the single DSA patient, haemostasis was achieved in 5mins.
- The haemostasis time in both groups was significantly shorter than the conventional method of applying manual compression
with cotton gauze, which usually requires around 20 mins to achieve haemostasis. - No re-bleeding from puncture sites was observed during the observation for additional 2-3 hours after removing the
manual compression. Similarly, the puncture sites showed no rebleeding, skin irritation, swelling, vascular complication,
allergy after the removal of Axiostat. - Further, there was no incidence of device-related bleeding complications during 5 days after the surgery.
Overall, Axiostat was also found to be an excellent haemostat dressing in patients undergoing transfemoral interventional
cardiology procedures.