100% Chitosan Haemostatic Dressing
Emergency Bleeding Control with Haemostatic Dressing
Axiostat is a sterile, non-absorbable haemostatic dressing intended to control bleeding within minutes of application by providing an active mechanical barrier to the wound site.
The emergency variant is designed to control moderate to severe bleeding due to traumatic injuries such as accidents. It is ready to use and can be cut to suit different wound sizes. It can be delivered through a pool of blood and is simple to apply and remove by a non-medical first responder.
Axiostat works on the principle of adhesion due to charge. Axiostat made with 100% chitosan has been designed to be positively charged and blood cells carry a net negative charge. When blood comes in contact with Axiostat, oppositely charged components are attracted and form bonds. This results in a strong adhesive seal that acts as a mechanical barrier preventing blood from leaking out.
- Sterile, ready to use
- Easy, painless removal
- Effective in patients on blood thinners
- Can be cut, folded, stuffed into deep wounds
Based on patented, clinically validated a.c.t (Axio clotting technology)
intended use / indication
Axiostat® is a sterile, single use, non-absorbable haemostatic dressing intended to be used for temporary control of bleeding wounds.
Axiostat® stops moderate to severe bleeding due to cuts, abrasions, lacerations, venous or arterial bleeding.
Neck and Head
Lacerations & deep cuts
|Composition||Chitosan - 100%|
|Indication||Stops moderate to severe bleeding|
|Mechanism||Charge-based mucoadhesion and |
|Material||Natural, Biocompatible, |
Positively- charged polymer
|Type||Highly absorbent sponge (absorbs |
minimum 30x its weight)
|Flexibility||Pliable, conformable to any wound |
shape, active on all sides
|Sterility||Sterilized using Gama irradiation|
|Shelf Life||3 Years|
|Removal||Irrigate with saline|
|Side Effects||No side effects|
reduces blood loss from traumatic injuries.
how to use axiostat
- Assessing the Efficacy of Haemostatic Dressing Axiostat in Trauma Care at a Tertiary Care Hospital in India: A Comparison with Conventional Cotton Gauze. Patel K. et al. Indian Journal of Emergency Medicine; 2016, 2(2):93-99.
- Studying Safety & Efficacy of AxiostatÂ® Dressing in Acute Hemorrhage Due to Trauma-Comparative Study. Kabeer M. et al., 2012. ClinicalTrials.gov Identifier: NCT03035695
- Toxicity and hemostatic potential of poly [ÃŸ-(1, 4)-2-amino-2-deoxy-D-glucosamine] based hemostatic material on albino rabbits. Mohanan PV, Mavely L, Pandya A. Toxicology Mechanisms and Methods; 2011, 21(1):25-30.
- Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Dai T. et al., Expert Review of Anti-infective Therapy; 2011, 9(7):857-879.
- Haemostatic dressings in prehospital care. Smith AH, Laird C, Porter K, Bloch M. Emergency Medicine Journal; 2013, 30(10):784-789.
- Local and systemic hemostatics as an adjunct to control bleeding in trauma. Georgiou C, Neofytou K, Demetriades D. The American Surgeon. 2013,79(2):180-7.
- Insights into the mode of action of chitosan as an antibacterial compound. Raafat D, von Bargen K, Haas A, Sahl HG. Applied and Environmental Microbiology; 2008, 74(12):3764-73.
- Hemostatic Agents Derived from Chitin and Chitosan. Whang H. S. et al., Journal of Macromolecular Science, Part C; 2005, 45 (4), 309â€“323.